The invention provides a substation secondary equipment configuration information exchange system and a method. The system comprises a main station end and a plurality of substation ends. A main station end comprise an operation and maintenance configuration tool and a virtual tunnel module, wherein that operation and maintenance configuration tool is communicatively connected with the virtual tunnel module; a substation operation and maintenance communication gateway is built in each substation end. The virtual tunnel module is communicatively connected with each substation operation and maintenance communication gateway, and each substation operation and maintenance communication gateway is communicatively connected with corresponding secondary equipment of the substation. The primary station is used for acquiring the configuration parameter information of the secondary equipment of the target substation, modifying the configuration parameter information, and then sending the modified configuration parameter information to the secondary equipment of the target substation. The invention can realize the remote modification of the configuration parameters of the secondary equipmentin a plurality of substations at the main station end, saves the personnel traffic time, avoids traveling among the plurality of substations, and improves the working efficiency.