The invention discloses anion-cation co-doped zinc oxide conductive powder and a preparation method thereof. The preparation method comprises the following steps: firstly, preparing aluminum, galliumor indium-doped basic zinc carbonate by a coprecipitation method, then mixing the basic zinc carbonate with aluminum fluoride or zinc fluoride powder, performing ball milling, and finally performing high temperature calcination under a reducing gas atmosphere. The anion-cation co-doped zinc oxide conductive powder has the following advantages: the surface dangling bonds of the zinc oxide powder isinactivated by doped fluorine atoms to inhibit the zinc oxide light-colored conductive powder from adsorbing oxygen from air, thereby greatly improving the stability of the zinc oxide powder; the fluorine atoms can also inhibit formation of deep defects in the zinc oxide light-colored conductive powder, thereby reducing absorption of the conductive powder on visible light and improving the whiteness of the conductive powder; and the fluorine atoms can provide one more electron after substituting oxygen atoms in a zinc oxide crystalline lattice, thereby improving the conductivity of the zinc oxide light-colored conductive powder. A product prepared by the method disclosed by the invention has the characteristics of high conductivity, high whiteness, good stability of resistivity, and the like, and is suitable to serve as a filler of an antistatic coating.