The invention discloses a machine learning-based simultaneous interpretation method and device. The machine learning-based simultaneous interpretation method comprises steps: the speech content and the speech characteristics of a target speaker are acquired; machine learning is used, and the speech characteristics of the target speaker are imitated; the speech content of the target speaker is translated to the speech content of a specified language; and the speech content for imitating the speech characteristics of the target speaker by the machine is outputted in the specified language, wherein the language of the target speaker and the specified language are different. The technical scheme of the invention has the advantages that automatic interpretation recognition can be realized, theinterpretation result is outputted by the speech characteristics of the target speaker, the interpretation result is more realistic, and the user experience is enhanced.