The invention discloses heat shock protein 90 inhibitor and application thereof in liver cancer treatment. Deodar cedar alcohol and frullania tamarisci terpene alcohol are discovered to be effective heat shock protein 90 inhibitors, can be used for inhibiting reproduction of liver cancer cells and inhibiting invasion of liver cancer cells by inhibiting heat shock protein 90, so that the deodar cedar alcohol and frullania tamarisci terpene alcohol can be developed into medicines for inhibiting focus growth of liver cancer or medicines for inhibiting liver cancer metastasis for liver cancer treatment. No technical scheme is disclosed in the prior art, and no technical enlightenment exist.