The invention discloses a precise temperature control machining device of an impeller of an automobile engine compressor. The precise temperature control machining device of the impeller of the automobile engine compressor comprises a workbench, a milling device and a clamping device. The milling device and the clamping device are fixed to the workbench. The milling device comprises a fixing frame, a lifting air cylinder, a milling motor and a milling cutter. The clamping device is arranged on the lower side of the milling device. The clamping device is provided with impeller clamps. A shaft sleeve portion of an impeller workpiece is arranged on a center locating shaft of the clamping device in a sleeving manner first of all, then the impeller workpiece is fixed through the impeller clamps, a lifting air cylinder is started to push a lifting plate to descend, the milling motor drives the milling cutter to rotate, the milling cutter makes contact with the impeller workpiece to conduct milling, after one line is machined, the lifting air cylinder drives the lifting plate to descend, the milling cutter is separated from the impeller workpiece, an adjusting motor rotates at the same time, so that the unmachined portion of the impeller workpiece is upward, and through such repeated operation, machining of the whole part is completed. The precise temperature control machining deviceis simple in structure, easy to operate and capable of conveniently and rapidly completing machining operation.