The invention relates to an adsorption desulfurization method of FCC gasoline. The FCC gasoline is cut into light and heavy gasoline fractions, the light gasoline fraction is in contact with an adsorption desulfurization catalyst, the adsorption desulfurization catalyst is prepared from, by weight, 25.0-50.0% of zinc oxide, 0.5-25.0% of nickel oxide, 2.0-55.0% of ZSM-5 molecular sieve, 20.0%-50.0%of macropore aluminum oxide and 1.0%-25.0% of cerium zirconium solid solution, the reaction process conditions are as follows: the reaction temperature is 180-320 DEG C, reaction pressure is 0.5-2.5MPa, the volume space velocity is 3-8 h<-1>, and the hydrogen oil volume ratio is 1-50. The breakthrough sulfur capacity of the catalyst is high, the olefin saturation ratio is low, and the regeneration and reduction stability is good.