The invention provides a method and device for determining advertisement bidding, a server and a storage medium. The method comprises the following steps of receiving an advertisement bidding request,wherein the advertisement bidding request carries identification information of a target advertisement space and user identification of a target user; obtaining an expected bid for the target advertisement to be bid; obtaining the click probability of the target user clicking on the target advertisement; determining a quality score of a target advertisement space, wherein the quality score of thetarget advertisement space is at least used to characterize a first probability that there is no advertisement cheating in the target advertisement space; according to the quality score of the targetadvertisement, the expected bidding price of the target advertisement and the click probability of the target user, determining the advertisement bidding price of the target advertisement. The schemeof the present application may be advantageous in improving the effectiveness of advertisement delivery.