Amido bond connected uracil-carbazole conjugates and synthesis and application thereof relate to the field of chemicals. A series of the amido bond connected uracil-carbazole conjugates are designed and synthesized by taking carbazole and uracil as the nucleus and according to active structure splicing principles. The amido bond connected uracil-carbazole conjugates are important heterocyclic compounds with good anti-tumor activity. Therefore, the invention discloses application prospects of the amido bond connected uracil-carbazole conjugates as anti-tumor drugs. The structural formula of theamido bond connected uracil-carbazole conjugates is shown as follows.