The invention relates to the technical field of early examination of tumor metabolism products in urine, in particular to a simple fast safe tumor screening compound. The simple fast safe tumor screening compound is prepared from an A solution, a B solution, a C solution and a D solution, wherein the A solution is a polyvinylpyrrolidone-tetrabromophenolphthalein ethyl ester potassium salt aqueoussolution, the B solution is a tween 80 aqueous solution, the C solution is an ethanol solution containing diethyl phthalate and ethyl acetate, and the D solution is a selenium dioxide aqueous solution. By means of the tumor screening compound, tumor metabolism products such as peptide and amino acid which exist in urine can be detected, the risk of strong acid, strong alkali and toxic heavy metalare overcome, and the simple fast safe tumor screening compound is safe and high in accuracy.