The invention provides spirit and brain refreshing ointment/oil, which includes, by mass, 20 g of fructus alpiniae oxyphyllae, 30 g of flos magnoliae, 20 g of mint, 6 g of costustoot, 20 g of sandalwood, 1 g of borneol, 15 g of radix angelicae, 20 g of prepared fleece flower roots, and 5 g of agastache rugosus. The ointment/oil is used for relieving discomfort symptoms, such as dizziness, headache, nausea, sleepiness, laziness and the like, of human body. The ointment/oil has the functions of refreshing spirit and brain, relieving pain and itch, and clearing heat and improving eyesight.