The invention relates to a preparation method and application of a wear-resisting high-temperature-resisting antiseptic coating for a dry type vacuum pump, and belongs to the technical field of coatings. The preparation method comprises the following steps that 1, a surface active agent and a cross linking agent are added into water, and stirring is performed till the agents are dissolved; 2, polyether ketone ketone fine powder is slowly added into step 1, meanwhile, after preliminary dispersion is performed through an emulsification machine, grinding dispersion is performed through a sand mill, and a product is obtained. The preparation method is scientific, reasonable and easy to implement, and the obtained anti-corrosive coating has the advantages of being resistant to wear, high temperature and corrosion, and excellent in anti-cracking performance. The application method of the anti-corrosive coating is easy to implement and facilitates construction.