The invention discloses a production method of a light-emitting cable, which comprises a step of extruding a light-emitting layer and a step of cooling the light-emitting layer. An atomization coolingstep is carried out between the step of extruding the light-emitting layer and the step of cooling the light-emitting layer. The cable with the extruded light-emitting layer passes through an atomization environment, and the diameter of atomization particles in the atomization environment is 0.25-0.5mum. According to the invention, the thickness of the light-emitting layer does not need to be increased, and the design size requirement of the cable can be guaranteed. The production cost of the cable can be reduced, and the surface of the light-emitting layer is roughened uniformly and finely after roughening treatment. The uniformity of the thickness of the light-emitting layer is guaranteed, and the light receiving capacity of the light-emitting layer is enhanced. The light-emitting intensity and the light-emitting time of the light-emitting layer are improved.