The invention discloses medicinal liquor prepared by adopting pits and dried fruits as well as a preparation method and application thereof. The medicinal liquor is prepared from the following raw materials: baijiu, a mixture of various pits and dried fruits and agilawood, wherein the pits and the dried fruits comprise dried grapes, dried mulberries, amygdaloid pits, longan pits, jujube pits, pawpaw pits and walnut inner skin, wherein the baijiu is maotai-flavor pure grain baijiu which is 53 degrees or above; preferably, the pits and the dried fruits are prepared from the following raw materials in weight: 45g of the dried grapes, 35g of the dried mulberries, 25g of the amygdaloid pits, 25g of the longan pits, 25g of the jujube pits, 25g of the pawpaw pits, 15g of the walnut inner skin and3g of the agilawood. The invention also provides the preparation method of the medicinal liquor prepared by adopting the pits and the dried fruits, and application of the prepared medicinal liquor. The medicinal liquor provided by the invention is also called purpurine fruit wine, is long in aftertaste, is capable of keeping fragrance lasting in a hollow cup, and has the effects of clearing heat,detoxifying, activating blood, removing blood stasis, consolidating basis, strengthening the body resistance, resisting oxidation and the like.