The invention relates to a deoxygenization and desulfurization filler filling method. The deoxygenization and desulfurization filler filling method comprises the steps: a high temperature and high pressure resistant deoxygenization and desulfurization filler is layered; a deoxygenization and desulfurization container capable of resisting to the high temperature and high pressure is filled with thedeoxygenization and desulfurization filler in a mode that an air flow to be deoxygenized and desulfurized can be allowed to circulate; the deoxygenization and desulfurization filler can move under the effect of the air flow to be deoxygenized and desulfurized to generate collision friction to remove oxide layer debris from the surface; and a reduction filler capable of reducing the oxide layer debris is laid at the bottom of the deoxygenization and desulfurization container in a filled mode. According to the method, the problems in the prior art can be solved, the method is easy to operate, by using the method for filling, the deoxygenization and desulfurization filler can be in an active state under the high temperature and high pressure environments to conduct deoxygenization and desulfurization, self-activation of the deoxygenation and desulfurization filler can be achieved, and the deoxygenation and desulfurization efficiency and the filler utilization rate are high.