The invention provides an anti-ionizing radiation container. The container includes an end cap and a container body, and the end cap is used for sealing the container body; and the container body includes a bottom wall and side walls fixedly connected with the bottom wall, the bottom wall and the side walls respectively comprise laminated plate bodies, each laminated plate body comprises an innerwall, a middle structure and an outer wall which are sequentially arranged from the interior to the exterior in an overlaid manner, the inner wall is a first fibrous resin material layer, the middle structure comprises second fibrous resin material layers and a metal layer alternately arranged from the interior to the exterior in an overlaid manner, and the outer wall is a third fibrous resin material layer. The invention also discloses a preparation method of the anti-ionizing radiation container.