The invention discloses a mimicry defense method based on inserted crosstalk information, and the existing network security defense method has static and passive defects and is easy to become a staticattacked target. The objective of the method is to use a mimicry defense method to detect attackers and return error information subjected to content scrambling to the attackers, so that the attack cost of the attackers is increased. The method comprises the following steps: firstly, checking the context of a content scrambling module; The method comprises the steps of obtaining a hyperlink, judging whether the request header is processed or not, then respectively processing the HTTP request header and an HTTP request packet body, adding the length of the mixed content on the original basis,then carrying out Javascript coding on the hyperlink, and finally defining the mixed content to complete the mixing of the response content. The provided method can realize dynamic defense for the server for unknown vulnerabilities and unknown attacks, and the steps are simple.