The embodiment of the invention discloses a power distribution network reliability index evaluation method, device and equipment. The method comprises the following steps of constructing a sample library matrix consisting of characteristic parameters and reliability indexes; performing normalization processing and clustering analysis on the sample library matrix and solving a normalized reliability index by utilizing a normal equation; and finally, subjecting the normalized reliability index to reverse normalization to obtain the power distribution network reliability index without relying onthe target grid topology information of the power distribution network, so that the technical problem that the calculation of the power supply reliability index of the existing power distribution network depends on the power distribution network system topology structure is solved.