The invention discloses a region division and dynamic adjusting method for a traffic road network. According to the method, features of change of congestion of internal roads of large-scale urban roadnetworks within different time periods are considered in combination with a traffic network traffic flow diffusion mechanism, through the traffic relevancy among adjacent signalized intersections andsimilarity among road sections, the road sections with similar traffic running states in the road network are distributed in same subareas, and the traffic control subareas are dynamically adjusted.The traffic state types of the control subareas are judged according to the real-time traffic flows, the road section queuing lengths and vehicle densities in the road sections of the signalized intersection, and theory and technique bases can be provided for macroscopic congestion network regional traffic flow coordination control; through the synthesis of road physical properties and congestiondiffusion mechanisms reflected by a macroscopic fundamental map, a clustering methodology is adopted for dividing the road network, and the validity of the division of the subareas is improved; a dynamic adjustment strategy is introduced, the isomorphism inside the control subareas is improved, the isomerism among the control subareas is improved at the same time, and a valid subarea division method is provided for the traffic road network.