The invention relates to an intelligent substation interoperability level evaluation method and system. The method comprises the steps of performing a simulation experiment according to a pre-established interoperability level simulation experiment system to obtain each level of interoperability experiment result; evaluating the interoperability level of each level of the intelligent transformer substation according to each level of interoperation capability experiment result; wherein the interoperability levels comprise an isolated level, a connected level, a function level, a domain level and an enterprise level; the interoperability grade simulation experiment system carries out simulation experiments on each grade of interoperability based on a set interoperability grade. Appropriate overall evaluation is conducted on the intelligent transformer substation, information such as the service requirement, the operation and maintenance requirement and the overhaul state of the intelligent transformer substation is accurately mastered, and information interaction standardization work of the intelligent transformer substation is guided.