The invention belongs to the technical field of pressure supplementing machine electromechanical tests, and particularly relates to a pressure supplementing machine electromechanical test device for acentrifugal uranium concentration process system. a compressed air inlet valve is respectively connected with a manual stop valve A and a manual stop valve B; the manual stop valve A and the manual stop valve B are respectively connected with an electric vacuum valve A and an electric vacuum valve B; the electric vacuum valve A and the electric vacuum valve B are respectively connected with a working buffer tank A and a working buffer tank B; a compressed air pressure gauge is mounted on a pipeline between the manual stop valve A and the manual stop valve B; a vacuum pump is respectively connected with a vacuum electromagnetic valve A and a vacuum electromagnetic valve B; and the vacuum electromagnetic valve A and the vacuum electromagnetic valve B are respectively connected with the working buffer tank A and the working buffer tank B. According to the pressure supplementing machine electromechanical test device for the centrifugal uranium concentration process system, a pressure supplementing machine is simulated to be in a no-load state, a load state and an overload state on a process system, and the operation conditions of a motor, a rotor and a bearing of the pressure supplementing machine are judged through parameters such as starting current, starting time and friction power consumption.