The application provides a station and room operation and maintenance monitoring system. By means of the conjunction of an equipment health state monitoring subsystem, an equipment file full-life management subsystem, an intelligent safety operation and maintenance monitoring and early warning subsystem, an operating environment state monitoring subsystem and an intelligent security protection subsystem, the station operation and maintenance monitoring system realizes intelligent security protection. The security protection system implements an intelligent integrated operation mode, and once an accident occurs, quickly locates an accident location, uploads the alarm information to a background platform, pushes images in the alarm area, and displays an alarm screen on a display screen in order that a worker can conveniently analyze and process an alarm site and an alarm situation.