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发明公开
CN109971860A 基于甲基化修饰的肿瘤标记物STAMP-EP8及其应用 有权

基于甲基化修饰的肿瘤标记物STAMP-EP8及其应用
摘要：
本发明提供了一种甲基化肿瘤标志物STAMP‑EP8及其应用，属于疾病诊断标记物领域。本发明提供了甲基化肿瘤标志物STAMP‑EP8在制备肿瘤诊断试剂中的应用。本发明所述肿瘤标志物STAMP‑EP8，在所有肿瘤类型中均高甲基化，对应的正常组织中均低甲基化，具有非常高的敏感性与特异性，检测所述STAMP‑EP8的引物可用于制备肿瘤诊断试剂盒。
摘要（英）：

The invention provides a methylation modification-based tumor marker STAMP-EP8 and application thereof and belongs to the field of disease diagnosis markers. Specifically, the invention provides application of the methylation modification-based tumor marker STAMP-EP8 to preparation of tumor diagnosis reagents. The methylation modification-based tumor marker STAMP-EP8 can be highly methylated in all types of tumors as well as lowly methylated in all corresponding normal tissues and achieve ultrahigh sensitivity and specificity; primers for detecting the methylation modification-based tumor marker STAMP-EP8 can be applied to preparing tumor diagnosis kits.

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