The invention discloses a processing method and device capable of reducing fatigue. The method includes: collecting bioelectric signals of a driver; processing the bioelectric signals of the driver toacquire fatigue degree of the driver; controlling a music unit and/or a vibration unit to run according to the fatigue degree of the driver, wherein the music unit is arranged in a vehicle and used for playing music to relieve fatigue of the driver, and the vibration unit is arranged on a driver's seat and used for vibrating to massage the driver to relieve the fatigue of the driver. Through theprocessing method and device, the problem that the fatigue of the driver is difficult to be relieved timely in related technology is solved.