The invention relates to the technical field of iron and steel, in particular to a hot-based spangle-free high-strength galvanized plate for a building structure and a production method thereof. A galvanized raw material with thickness being 1.0-3.0 mm is provided by an ESP production line, and then a technology including pickling, leveling, heating, galvanizing, finishing and rolling is carried out through a PGL pickling and galvanizing continuous production line to form a a hot galvanized roll. According to the production method, a component of conventional low-carbon soft steel is utilized,control is carried out through an acid plating technology, a spangle-free galvanized plate with the thickness being 1.0-3.0 mm and the weight of a zinc layer being 60-275g/m2 is produced, and the performance control in the range of 280-380 MPa of the yield strength (Rp0.2), 320-450 MPa of the tensile strength and 23-35% of the elongation can be realized.