The invention discloses an e-commerce multi-target bidding quotation strategy calculation method considering a bidding winning probability. The method comprises the following steps: S1, fitting a historical clearing quotation distribution curve of an e-commerce; S2, calculating the bidding winning probability of different bidding behaviors of the electricity seller; S3, constructing an e-commerceoperation target set; and S4, calculating an optimal quotation strategy of the electricity seller according to the operation target of the electricity seller. According to the method, a multi-target bidding model is established by combining the bidding probability to effectively simulate the bidding behavior of the e-commerce, and an optimal bidding strategy is obtained.