The invention belongs to the field of optical micro-structures, and particularly relates to a pressure detection structure based on an optical signal, and a use method thereof. The pressure detectionstructure is provided with a substrate layer, a flexible material layer and a metal micro-nano structure layer in sequence from bottom to top, wherein the metal micro-nano structure layer is providedwith at least one through hole; each through hole is full of flexible substances; and a chiral metal micro-nano structure is fixed on the flexible substances, and the thickness of the flexible substances is greater than the thickness of the metal micro-nano structure layer. Through the arrangement of the flexible substances and the flexible material layer, the chiral metal micro-nano structure isarranged above the flexible material, a certain height difference is formed between the chiral metal micro-nano structure and the through hole, coupling is mainly centralized in a longitudinal direction instead of a horizontal direction, and a new thought is provided for designing a planar chiral structure.