The technical scheme discloses an in-mold label manufacture process and an in-mold label thereof. The in-mold label manufacture process includes the steps of protection layer and base material layer compounding and melting layer and base material layer compounding. The in-mold label comprises a base material layer, a protection layer and a melting layer. The face, where pattern identification is printed, of the base material layer is the front face, and the other face of the base material layer is the back face. The protection layer is arranged on the front face of the base material layer. Themelting layer is arranged on the back face of the base material layer. The in-mold label manufacture process is completed on one two-sided laminating machine, most of auxiliary materials are omittedwhile excessive working procedures are omitted, and therefore the manufacture cost is greatly reduced, energy consumption and emission reduction are achieved, and environment pollution is reduced; andthe working procedures are simple and mature, operability is high, and the weather-proof performance of the in-mold label and comprehensive performance of products are improved compared with those ofthe existing process.