The invention discloses an intelligent decision-making and design system and method for a grinding disc of a disc mill for pulping and papermaking. The system comprises a human-computer interaction interface, a demand index evaluation module, a quality function expansion module, a problem recognition module, a mathematical model library module, a design scheme evaluation module, a system connection module and an abrasive disc computer aided design platform module. A database, a knowledge base and an abrasive disc design parameter machine learning sub-module supported by the knowledge base arearranged below the mathematical model library module. the method comprises: after a demand is received, organizing the demand into a demand index; determining the importance degree of the user demandelements according to the demand index evaluation model; respectively converting requirements into slurry characteristic requirements and abrasive disc design requirements; defining a grinding problemthrough grinding piece design requirements, determining a grinding mode and a grinding tooth type, generating grinding piece design main parameters by applying a grinding piece prediction model, quantitatively evaluating the generated grinding piece scheme, inputting grinding piece scheme ideal solution parameters into a grinding piece CAD system, and generating a grinding piece three-dimensionalmodel. The research and development period of the abrasive disc is shortened and the research and development cost is reduced.