The invention discloses a wet recovery method of large-block high-temperature alloy waste, and belongs to the field of wet metallurgy. The method comprises the following steps that the large-block high-temperature alloy waste is machined into high-temperature alloy chips, then the chips are put into a mixed solution of hydrochloric acid, nitric acid and distilled water, and the liquid-solid ratiois (5-10) ml: (1-2) g, then 2-20 mL of a reagent A is added, wherein the reagent A is one or more of an oxalic acid solution, a citric acid solution and hydrogen peroxide, dissolving is conducted for1-5 hours under a stirring condition, and solid-liquid separation is further conducted after dissolution so as to realize classified separation of different elements. According to the method, the dissolution rate of a large-block high-temperature alloy can be increased, obstruction of a passivation film in a high-temperature alloy dissolution process is solved, and a contact area of the high-temperature alloy and leachate is greatly expanded; and meanwhile, raw materials are waste high-temperature alloys, the oxalic acid solution, the citric acid solution and the like are cheap and easily available, a recovery process is simple and controllable, large-scale production is facilitated, and the method has good practicability and economic prospects.