The invention discloses a delayed coking raw material, a pretreatment method thereof, petroleum coke and a preparation method of the petroleum coke. The pretreatment method comprises following steps:the delayed coking raw material is subjected to cavitation oxidation treatment with an oxidant-catalyst, then the delayed coking raw material is subjected to visbreaking treatment, and therefore, sulfur difficult to decompose in the delayed coking raw material is converted into sulfone and oxysulfide gas which are easy to decompose. Synchronous production and desulfurization of the petroleum cokein the delayed coking process are realized, an existing petroleum coke desulfurization technology is greatly simplified, and the problem of high cost of first production and later refining desulfurization is effectively solved.