The invention provides an anhydrous solvent type cleaning agent. The cleaning agent is prepared from components of raw materials in parts by weight as follows: 55-95 parts of isohexane, 1-20 parts ofalcohols, 1-20 parts of esters, 1-5 parts of D-limonene, 0.5-5 parts of a surfactant, 0.05-5 parts of a detergent and 0-0.05 parts of essence. Compared with the prior art, the anhydrous solvent type cleaning agent is prepared from specific content of components of the raw materials capable of realizing better interaction. The product has a higher removal effect on oily and water-based dirt, is high in drying speed, has no residues on the surface, does not damage fiber of clothes, does not contain carcinogenic benzene homologues, chlorine compounds or other toxic and harmful volatile matter, has a small influence on the environment, is convenient and rapid to use and can be popularized and used in all garment factories.