The invention discloses a foundation vibration isolation and three-dimensional damping structure for a double-layer containment nuclear power station. The foundation vibration isolation and three-dimensional damping structure comprises an inner containment, an outer containment, a reactor core supporting structure, a reactor core structure, a horizontal seismic isolation support, a hydraulic transmission mechanism, a vertical seismic isolation support and a vertical damper, wherein the inner containment and a foundation are connected through the horizontal seismic isolation support, a bearingcomponent of the reactor core structure is connected with the bottom plate of the inner containment through the vertical seismic isolation support, the bearing component of the core structure is connected with the side wall of the inner containment through the vertical damper, and the inner containment and the outer containment are connected through the hydraulic transmission mechanism. Accordingto the foundation vibration isolation and three-dimensional damping structure for the double-layer containment nuclear power station, the horizontal vibration isolation support, the hydraulic transmission mechanism, the vertical vibration isolation support and the vertical damper are arranged, so that the three-dimensional damping effect is achieved, the special anti-seismic safety requirement ofthe nuclear power station can be met, and the anti-seismic safety of the nuclear power station structure is remarkably improved.