The invention relates to a manufacturing method for quickly processing municipal solid waste and derivatives at the high temperature. The manufacturing method is characterized in that the municipal solid waste, waste plant powder, kitchen waste, quick lime, ferrous sulfate, magnesium sulfate and chlorine dioxide are uniformly mixed, sealed high-temperature fermentation equipment is adopted, the temperature of the interior of the fermentation equipment is increased to 100 DEG C through oil-electricity heat conducting and keeps for 2 hours, the temperature is kept at 60-80 DEG C, a thermophilicanti-high-temperature active multiple species inoculant is added for fermentation, the intermittent stirring function of a fermentation machine stirring system is performed, the municipal solid wasteferments in the fermentation machine for 12 hours, and harmful microorganism eggs, weed seeds and pathogenic bacteria in the municipal solid waste are effectively killed; the fermented clinker is madeinto powder through an ageing smashing screen, and the powder is weighed by an automatic electronic scale and packaged into organic matter products through packaging machine; and accordingly, the municipal solid waste disposal problem is solved, recycling comprehensive utilization of the municipal solid waste is achieved, and pollution to the natural environment is reduced.