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发明公开
CN110101874A 一种利用HGF转基因的干细胞治疗ARDS的方法 审中-实审

一种利用HGF转基因的干细胞治疗ARDS的方法
摘要：
本发明公开了一种利用HGF转基因的干细胞治疗ARDS的方法，本发明利用携带有人肝细胞生长因子(HGF)的重组间充质基质干细胞(mesenchymal stromal cells，MSC)在治疗急性呼吸窘迫综合征(acute respiratory distress syndrome,ARDS)或制备治疗ARDS药物中的应用。本发明提供了一种新的ARDS治疗方法，利用HGF修饰过的MSC治疗ARDS，使得MSC对ARDS的治疗更有针对性，预防减少MSC对无适应症ARDS患者应用后可能会产生的有害性纤维化副作用，增强MSC临床治疗效果。
摘要（英）：

The invention discloses a method for stem cell treatment ARDS by means of HGF transgenosis. The invention provides application of mesenchymal stromal cells (MSC) carrying hepatocyte growth factor (HGF) for treating acute respiratory distress syndrome (ARDS) or preparing medicine for treating ARDS. The invention provides a novel ARDS treatment method. The ARDS is treated by means of the HGF modified MSC, the MSC has the more pertinence for ARDS treatment, harmful fibrosis byproducts possibly generated after non-indication ARDS patients apply the MSC are prevented and reduced, and the MSC clinictreatment effect is enhanced.

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