An embodiment of the invention provides an experiment designing management method and a device, wherein the method comprises the steps of acquiring an experiment parameter; storing the experiment parameter in a first preset path so that an experiment designing device can acquire the experiment parameter in the first preset path, generating an orthogonal table based on the experiment parameter, andstoring the orthogonal table in a second preset path; acquiring the orthogonal table in the second preset path, and generating an experiment sequence based on the orthogonal table. The method and thedevice according to the embodiment of the invention are not restricted by equipment and researching personnel. Orthogonal experiment designing is automatically executed. The experiment sequence can be obtained just through the experiment parameter. Researching personnel cannot perform modification midway, thereby preventing a condition of incapability of obtaining an optimal combination caused byrandom experiment instance deleting for saving experiment time, and supplying quality insurance for experiment execution.