The invention provides a video deblurring method and device based on double exposure priori, and the method comprises the following steps: (A), designing a double exposure mode of a camera, and obtaining a video with continuously alternated long-short exposure frames; (B) carrying out brightness stretching on the short exposure frame in the acquired video; (C) setting a double-exposure prior item,and constructing a deblurring overall equation of the long-exposure blurred frame; (D) solving the long exposure frame deblurring equation by adopting a semi-quadratic splitting method to obtain a blurring kernel; (E) restoring the long exposure fuzzy frame by adopting a non-blind deconvolution algorithm, and restoring the deblurred long exposure frame; and (F) circularly executing the steps B toE until all long exposure frames are processed, and obtaining a final deblurred clear video. According to the method, the blurring kernel can be accurately estimated, the finally recovered video image sequence has a good visual effect, and the video deblurring efficiency is remarkably improved.