The invention discloses a large-diameter multi-layer coil assembling, welding and conveying anti-deformation device and a use method, and belongs to the field of large container manufacturing. The difficulties of large-diameter multi-layer coil assembling, welding and conveying in the prior art are overcome. The anti-deformation device structurally comprises base channel steels 1, stud nuts 2, connecting plates 3, support channel steels 4, fixed-distance channel steels 5, tensile ribs 6, internal fixing angle steels 7 and external fixing angle steels 8; the eight base channel steels 1 are assembled and welded into an octagonal bottom bracket; the support channel steels 4 are mounted and fixed on the eight fixed-distance channel steels 5 through the connecting plates 3 for holding coils; connection of the fixed-distanced channel steels 5 and the base channel steels 1 is reinforced through the tensile ribs 6 from the two sides; the eight internal fixing angle steels 7 and the eight external fixing angle steels 8 support inside and outside and are connected with the eight base channel steels 1. The coils are mounted on the support channel steels 4 and assembled and welded from insideto outside and from bottom layer to top layer. The anti-deformation device is suitable for positioning of the large-diameter inner and outer double-ring coils during assembling and welding, the coil assembling and welding difficulty is lowered, and the effect that the coils are not deformed during conveying can be ensured.