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发明公开
CN110139873A HPV特异性结合分子 无效 - 撤回

HPV特异性结合分子
摘要：
提供了诸如TCR或其抗原结合片段和抗体及其抗原结合片段的结合分子，比如识别或结合包括HPV16 E6和HPV16 E7在内的人乳头瘤病毒(HPV)16的那些结合分子。还提供了含有这样的结合分子的工程化细胞、含有所述结合分子或工程化细胞的组合物、以及治疗方法，所述治疗方法例如施用所述结合分子、工程化细胞或组合物。
摘要（英）：

Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV)16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.

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