The invention belongs to the technical field of geotechnical engineering, and specifically relates to a 3D printing-based multi-coupling seepage test system and method for complicated fractal fractures. According to the system and method, a seepage test device is provided and a 3D printing method is adopted, so that test samples with different types or characteristics can be conveniently constructed, thereby adapting to the test requirements of various types of fractured rock masses. Through the test device, a test is carried out through changing different samples, so that the seepage characteristics of different rock masses can be measured. Through adjusting the water storage depth in a water tank, different water pressures can be obtained to test the samples. Through opening and closingseepage valves at different positions, the seepage characteristics of the samples in one direction or multiple directions can be tested. According to the 3D printing-based multi-coupling seepage testsystem and method for the complicated fractal fractures, the seepage characteristics closer to real complete rock masses can be simulated, so that theoretical direction and referential significance are provided for the design and construction of the underground projects.