The invention relates to the technical field of tablet candies, and specifically relates to a red yeast rice and natto tablet candy and a preparation method thereof. The candy is prepared from the following raw materials: red yeast rice powder, natto powder, lotus leaf instant powder, hawthorn powder, a disintegrating agent, an anti-sticking agent, maltodextrin, a binder, a lubricant and a coatingagent. According to the tablet candy and the preparation method thereof of the invention, the tablet candy prepared from the combination of the natto powder, red yeast rice powder, lotus leaf instantpowder and hawthorn powder can regulate blood lipids, and enhance immunity, has certain effects of dissolving blood clots, removing blood lipids, preventing arteriosclerosis and lowering uric acid inblood, and is better in taste.