The invention relates to a mobile application three-dimensional defense method and system. According to the method, software security technology is deployed on a mobile device, communication securitytechnology is deployed in the communication process of the mobile device. Risk control technology is deployed on a mobile application server, and a mobile application is comprehensively protected through the software security technology, the communication security technology and the risk control technology. Defense strategies in three aspects of the mobile device, information transmission and service provision are included. A plurality of parts including security reinforcement, security detection, security development, trusted computing, security transmission, risk control and channel monitoring are covered. The whole period of development, publishing, operation and communication of the mobile application is included. Comprehensive protection can be provided for the mobile application, thesecurity level of the mobile internet is improved. The occurrence rate of privacy disclosure and anonymity risks is reduced, and a complete and effective defense system is built for the mobile application.