The invention relates to cleaning equipment for a membrane separation apparatus. The membrane separation apparatus comprises a first membrane assembly and a second membrane assembly, and the cleaningequipment comprises a liquid storage tank, a first solenoid valve, a second solenoid valve and a controller, wherein the liquid storage tank is used for storing a cleaning medium, the liquid storage tank has a liquid outlet and a liquid inlet, the liquid outlet respectively communicates with a liquid inlet end of the first membrane assembly and a liquid inlet end of the second membrane assembly, the liquid inlet respectively communicates with a liquid outlet end of the first membrane assembly and a liquid outlet end of the second membrane assembly, and the controller is electrically connectedrespectively with the first solenoid valve and the second solenoid valve. The controller first controls the first solenoid valve to be opened and the second solenoid valve to be closed, the first membrane assembly is cleaned, after the cleaning is finished, the controller controls the first solenoid valve to be closed and the second solenoid valve to be opened, and the second membrane assembly iscleaned. Manual cleaning of the membrane separation apparatus is not needed, the radiation threat of radioactive materials remaining on the membrane separation apparatus to the cleaning personnel is avoided, and the labor cost is reduced.