The invention provides an aging life prediction method for a pipeline system sealing structure and a compression tool. The method comprises the following steps of: (1) compressing a sealing structureto be tested; (2) performing constant-temperature aging on the sealing structure to be tested in a compressed state, and testing whether the sealing structure to be tested is invalid at the same timeinterval; and (3) determining the aging life of the sealing structure to be tested according to the original parameters and the parameters after failure of the sealing structure to be tested. The invention relates to an aging life prediction method of a sealing structure of a pipeline system. In the technical scheme provided by the invention, the actual application environment of the sealing structure to be tested is simulated by compression and aging of the sealing structure to be tested until the sealing structure to be tested fails, and finally, the aging life of the sealing structure to betested is obtained by comparison, analysis and calculation of the original data of the sealing structure to be tested and the data after failure. The method is simple in step and accurate in prediction, can accurately determine the aging life of the sealing structure, and provides a powerful data reference and support for the design of a pipeline system.