The invention provides a nuclear power plant control room comprehensive information display system and method. The system comprises a display module and a nuclear power plant monitoring module connected with the display module, the display module comprises multiple display sub-modules, and the display sub-modules display nuclear power plant information in the same area, the nuclear power plant monitoring module is used for controlling each display sub-module to display the corresponding nuclear power plant information when a nuclear power plant runs normally; under the nuclear power plant accident working condition, one of the display sub-module is controlled to perform sound and light alarm, and another display sub-module is controlled to display alarm information synchronously. Accordingly, all nuclear power plant safety parameter display system parameters of the nuclear power plant are easily, rapidly, reliably, continuously and fixedly displayed, an operator can monitor and rapidlyknow the state of the nuclear power plant conveniently, and information processing and nuclear power plant control are efficiently conducted.