The invention provides a multi-network node configuration method and device, terminal equipment and a computer readable medium. The method comprises the following steps: determining a plurality of alternative network databases and respective corresponding active time periods thereof; selecting one of the plurality of alternative network databases of which the active time period is matched with thecurrent time as a network database to be accessed; and loading the configuration information of the network database to be accessed so as to access the network database to be accessed. Compared withthe prior art, the method has the advantages that the alternative network database matched with the current time can be selected to be automatically accessed according to the active time period of thealternative network database, so that the dependence on manual operation is avoided, the utilization rate of multiple network nodes and the network database switching efficiency can be improved, andthe service in the to-be-accessed network database is ensured to be carried out smoothly.