The invention provides an ink supply device and printing equipment. The ink supply device comprises an ink jet assembly, at least one color mixing roller and an ink uniformization assembly. The ink jet assembly comprises at least one ink bucket and at least one ink jet opening communicating with the ink buckets. Each color mixing roller is correspondingly arranged on one side of the ink jet assembly so as to bear ink jet out by the ink jet openings, and pot color areas are formed on each color mixing roller. The ink uniformization assembly comprises at least one ink uniformization roller, eachink uniformization roller is arranged on one side of the corresponding color mixing roller, and at least one point color area on the color mixing roller is uniformized into a solid color area throughthe ink uniformization rollers. Through the technical scheme, areas in patterns printed through the color mixing rollers are solid textures, newly-printed patterns have smoother edges, lines are clearer, and colors are more real. In addition, ink flows to the color mixing roller from an ink fountain, and the situations of ink return and contamination of ink of the ink buckets are avoided.