The present invention discloses a direct current mutual inductor wireless calibration device and method based on GPRS communication. The device comprises a plurality of calibration systems, each of the plurality of calibration systems includes: a GPRS wireless communication module, a wireless synchronization module, a measurement acquisition module, and a data processing module; wherein the GPRS wireless communication module is configured to perform wireless communication with other calibration systems; the wireless synchronization module is configured to receive a high-precision satellite timing synchronization signal, and to send the synchronization signal to the measurement acquisition module; the measurement acquisition module is configured to trigger data collection according to the synchronization signal; and the data processing module is configured to perform time-scale alignment to pre-processed data and the data received by the GPRS wireless communication module, and perform comparison calculation, to obtain a calibration result of a direct current mutual inductor to be tested. The device and method solves the problem of voltage loss and long-distance asynchronous calibration caused by long distance wiring difficulties and analog signals long-distance transmission during direct current mutual inductor field calibration