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发明公开
CN110305867A 调控脂肪干细胞干性维持能力的方法及其试剂 有权

调控脂肪干细胞干性维持能力的方法及其试剂
摘要：
本发明涉及调控脂肪干细胞干性维持能力的方法及其试剂，发现LncRNA-TCONS在脂肪干细胞干性维持过程中起了重要的调控作用，当LncRNA-TCONS下调，脂肪的增殖、干性维持能力均受到抑制，由此确认LncRNA-TCONS可作为多能干细胞干性维持的潜在靶点，可以用于开发出新的关于LncRNA-TCONS相关药物。
摘要（英）：

The invention relates to a method for regulating the dry maintenance ability of adipose-derived stem cells and a reagent. It is found that LncRNA-TCONS plays an important regulating role in the process of dry maintenance of the adipose-derived stem cells, the proliferation and the dry maintenance ability of adipose are both inhibited when the LncRNA-TCONS is lowered, thus the LncRNA-TCONS can be used as a potential target for dry maintenance of multipotential stem cells, and the method can be used for developing new related drugs about the LncRNA-TCONS.

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