The invention relates to a method for extracting polyphenolic components from grape skin seeds, which belongs to the technical field of food industry. The method firstly grinds and pulverizes the grape skin seed, and then removes the skin seed oil ester by supercritical carbon dioxide extraction, and extracts with an alkaline ethyl acetate mixed solution, performs underpressure distillation and recovery with an ethyl acetate phase, and finally obtains a grape polyphenol component. The method uses the skin and seed waste generated during the grape plantation and wine making processes, and is beneficial to the recycling resources of a planting industry and a wine industry. In the extraction process, only ethyl acetate and a NaOH solution with low concentration are used as extraction reagents, no other organic solvents, inorganic acids or color-protecting agents are used, after the ethyl acetate is subjected to underpressure distillation and recovery, ethyl acetate is reused, polluting ofthe environment is not generated, so that the process is green. The polyphenol component is protected by the ethyl acetate phase, and the antioxidant activity and the ability to scavenge free radicals are effectively protected. Therefore, the overall process scheme is an efficient, simple, safe and pollution-free method for extracting polyphenols.