The application of the invention provides a composition for preventing and treating alcoholic liver diseases and a preparation method and application of the composition. The composition comprises 0.1-1 part by weight of vitamin C, 0.5-5 parts by weight of succinic acid, 1-2 parts by weight of fumaric acid, 0.1-5 parts by weight of L-glutamin and 0-5 parts by weight of a radix salviae miltiorrhizaeextract. Through pharmacodynamics experiment of a drunk mouse model, the inventor can observe that the composition disclosed by the invention has obvious capacity for maintaining or improving drunk clear-thinking degree and motor coordination, and obvious effects of neutralizing the effect of alcoholic drinks, has a certain effect of alleviating liver damage caused by drinking, and can exert theeffect of nourishing the liver and/or protecting the liver.